I would be interested in finding out if the people that they are studying are also in therapy for their depression. I don’t think that anti-depressants alone work. I think that one needs therapy as well. You do need to get to the root problem of what’s causing your depression. But I will tell you that a few years ago I went on a low-dose of Zoloft and it helped me immensely. I was only on it a year but it along with therapy changed my outlook on life.